Study Review: Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age

Study: http://www.pkdiet.com/pdf/LifeExtMice.pdf

Energy Macro Percent Usage

Diet	Carbs	Fats	Protein
0.43% Methionine	69.6%	8.1%	12.5%
0.15% Methionine	69.9%	8.1%	12.3%

Historic charts show Methionine restricted mice lived longer.

Criteria	Score	Comments
One Constant Macro	*****	Diets were almost identical, with exception of the Methionine.
Constant Nutrients + Fiber	*****	Diets were almost identical, with exception of the Methionine.
Number of animals per diet	*****	43 mice were used per diet.
Length of Study	*****	1200+ days. The whole length of the mouse life.
Funding Bias	*****	NIA grants and American Federation for Aging Research Grant
Total	5.0	Good Quality Study