Study Review: Fructose decreases physical activity and increases body fat without affecting hippocampal neurogenesis and learning relative to an isocaloric glucose diet

Study: https://www.nature.com/articles/srep09589.pdf

Energy Macro Percent Usage

Diet	Carbs	Fats	Protein
Glucose	62.5%	18.3%	19.2%
Fructose	62.3%	18.2%	19.5%

Historical charts show the Fructose fed mice had more weight gain, and were less active than the Glucose fed mouse.

One Constant Macro	*****	Cumulative change of all macros is 0.6%
Constant Nutrients + Fiber	*****	Vitamins, Minerals, and Fiber was the same.
Number of animals per diet	***	12 animals per diet
Length of Study	*	77 days
Funding Bias	*****	Grant from Center for Nutrition, Learning and Memory
Total	3.8	Fair Quality Study