Study Review: Defining high-fat-diet rat models: metabolic and molecular effects of different fat types

Study: http://cancerres.aacrjournals.org/content/canres/71/13/4484.full.pdf

Energy Macro Percent Usage

Diet	Carbs	Fats	Protein
Normal	65%	11%	24%
High Fat	36%	45%	19%

Criteria	Score	Comments
One Constant Macro	***	Protein changes by 5%
Constant Nutrients + Fiber	*	Carb Types, Vitamins, Minerals, Fatty Acids, and Amino Acids all changed.
Number of animals per diet	***	"6–12 animals"
Length of Study	**	12 weeks
Funding Bias	*****	Grant provided by Else Kröner-Fresenius Foundation The food industry was not involved.
Total	2.8	Poor Quality Study